HISTORIA SOBRE EL PAPEL DE LAS HORMONAS Y LOS ANTICONCEPTIVOS EN EL LUPUS

Autores/as

  • Édgar Peñaranda-Parada Universidad Nacional de Colombia
  • Federico Rondón-Herrera Universidad Nacional de Colombia
  • José Félix Restrepo-Suárez Universidad Nacional de Colombia
  • Gerardo Quintana Universidad Nacional de Colombia
  • Antonio Iglesias-Gamarra Universidad Nacional de Colombia

Palabras clave:

Anticonceptivos hormonales, lupus eritematoso sistémico, oral contraceptives, systemic lupus

Resumen

Resumen

Tarea difícil y prolongada sería revisar la literatura para aquellos que quieran conocer el inicio de una serie de descubrimientos acerca de hormonas y lupus. Ante esto, nos hemos propuesto el objetivo de encontrar datos acerca de cómo las hormonas pueden tener una relación con la patogénesis del lupus. De esta manera hemos revisado los artículos publicados desde el inicio del siglo XX hasta su final, para poder recabar y poner en un orden esos descubrimientos y reconocer los méritos de los diferentes investigadores.

Palabras clave: Anticonceptivos hormonales, lupus eritematoso sistémico.

Historic View on the Role of Hormones and Hormonal Contraceptives in Pathogenesis of Systemic Lupus Abstract

Those interested in knowing a number of discoveries that link hormones and systemic lupus could face a long and troublesome search. This way, our objective in paper is to find data that shows an effect of hormones in lupus pathogenesis. Articles published on the subject since the beginning of the 20th Century until its end, were reviewed. Importance of discoveries and merits of different investigators were placed in perspective.

Key words: oral contraceptives, systemic lupus.

Biografía del autor/a

Édgar Peñaranda-Parada, Universidad Nacional de Colombia

Residente en Reumatología, Universidad Nacional de Colombia

Federico Rondón-Herrera, Universidad Nacional de Colombia

Especialista en Reumatología, Profesor Asociado Facultad de Medicina, Universidad Nacional.

José Félix Restrepo-Suárez, Universidad Nacional de Colombia

Especialista en Reumatología, Profesor Titular Facultad de Medicina, Universidad Nacional.

Gerardo Quintana, Universidad Nacional de Colombia

Especialista en Reumatología, Profesor Asistente Facultad de Medicina Universidad Nacional

Antonio Iglesias-Gamarra, Universidad Nacional de Colombia

Especialista en Reumatología, Profesor Titular Facultad de Medicina, Universidad Nacional

Referencias bibliográficas

Baehr G, Klemperer P, Schifrin A. A Diffuse Disease of the Peripheral Circulation Usually Associated with Lupus Erythematosus and Endocarditis. Trans. Ass Amer Physicians 1935; 50: 139-155.

Mattras A. Zur Symto matologie und klinik födlich verlaufender fälle von Lupus Erythematosus. Arch f. Dermat. u syph 1938; el XXVIII; 223-235.

Keil H. Dermatomyositis and Systemic Lupus Erythematosus II. Comparative Study of Essential Clinicopathologie Features. Arch Intern Med 1940; 66: 339-383.

Rose E, and Pillsbury DM. Lupus Erythematosus (Erythematodes) and Ovarian Function; Observations on Possible Relationship with Report of 6 cases. Ann Intern Med 1944; 21: 1022-1034.

Jarchos S. Lupus Erythematosus Associated with visceral Vascular Lesions; seriesof Autopsied Cases. Bull. Johns Hopkins Hospi 1936; 59: 262-273.

Dubois EL, Commons RR, Star P, Stein CS, Morrison R. Corticotropin and Cortisone Treatment for Systemic Lupus Erythematosus. J.A.M.A 1952; 149: 995-1002.

Engstrom WW, Munson PL. Studies on the Metabolism of Testosterone in Normal Women in Different Phases of the Menstrual Cycle. J Clin Endocr 1951; 11: 427-433.

Lamb JH, Lain ES, Keaty C, Hellbaum A. Steroid Hormones; Metabolic Studies in Dermatomyositis, Lupus Erithematosus, and Polymorphic Light-Sensitive Eruptions. Arch Derm 1948; 57: 785-801.

Koets P. Excretion of Urinary 17 Ketosteroids in Chronic Lupus Erythematosus: Case Report, Stanford Med Bull 1951; 9: 256-259.

Burch PRJ, Rowell NR. Autoimmunity, A etiological Aspects of Chronic Discoid and Systemic Lupus Erythematosus, Systemic Sclerosis, and Hashimoto’s Thyroiditis. Some Immunological Implications. Lancet 1963; 2: 507-513.

Burch PRJ, Rowell NR. Systemic Lupus Erythematosus. Etiological Aspects. Amer J Med 1965; 38: 793-801.

Kellum RE, Haserick JR. Systemic Lupus Erythematosus. A Statistical Evaluation of Mortality Based on a Consecutive Series of 299 patients. Arch Int Med 1964; 113: 200-207.

Iglesias- Gamarra A. Historia del lupus. Editorial Panamericana. Formas e impresos. Bogotá, agosto de 2003.

Finley WH, Finley SC, Beetham WP, Holley HL. Chromosome Studies in Systemic Lupus Erythematosus (SLE). Abs. Arthritis Rheum 1964; 7: 307.

Finkbiner RB, Decker JP. Ulceration and Perforation of the Intestine Due to Necrotzing Arteriolitis. New Eng J Med 1963; 268: 14-18.

Dubois EL. Lupus Erythematosus. University of Southern California Press, Los Angeles 1974: p137

Stern R, Fishman J, Brushman H, Kunkel HG.Systemic lupus Erythematosus associated with Klinefelter’s syndrome. Arthritis Rheum 1977; 20: 18-22.

French MAH, Hughes P. Systemic lupus Erythematosus and Klinefelter’s syndrome. Ann Rheum Dis 1983; 42: 471-473.

Ellis H.Marie Carmichael Stopes: Pioneer of birth control for women. Brit J. Hosp Med 2008; 69: 595.

Pincus G. The Control of Fertility. Academic Press, New York, 1965.

Lamb JH, Lain ES, Keaty C, Hellbaum A. Steroid Hormones; Metabolic Studies in Dermatomyositis, Lupus Erithematosus, and Polymorphic Light-Sensitive Eruptions. Arch Derm 1948; 57: 785-801.

Pederson T. A Good Man: Gregory Goodwing Pincus. The FASEB Journal 2009; 23: 2341-2344.

Marks L. Historia de la píldora anticonceptiva. Ciencias 1997; 48: 33-39.

Ansar S, Penhale WJ, Talal N. Sex Hormones, Immune Responses, and Autoimmune Diseases Mechanism of Sex Hormone Action. Am J Pathol 1985; 121: 531-551.

Shampo MA, Kyle RA. John Rock: Pionner in the Development of Oral Contraceptives. Mayo Clin Proc 2004; 79:844.

Advisory Committee on Obstetrics and Gynecology. “Report on the Oral Contraceptives”. Food and Drugs Administration. U.S. Department of Health, Educationand Welfare September 1969.

Hellman LM. The Oral Contraceptives in Clinical Practice. Family Planning Perspectives 1969; 1: 13-17.

Advisory Committee on Obstetrics and Gynecology. “Report on the Oral Contraceptives”. Food and Drugs Administration. U.S. Department of Health, Education and Welfare August 1, 1966.

Mintz M. The Pill. Columbia Journalism Review (in two parts: Winter 1968-1969 and Spring 1969)

Hart MH. The 100: A Ranking of the Most Influential Persons in History. Citadel Press, New York 1978

Alonso G. Historia de la anticoncepción. Rev Cubana Med 1995.

Hechter O. Homage to Gregoy Pincus. Perspectives Biol. Med. 1968; 11: 358-370.

Djerassi C. This Man `s Pill: Refl ections on the 50th Anniversary of the Pill. Oxford University Press, New York, 2001.

Royal College of General Practitioners. Oral contraception study: mortality among oral contraceptive users. Lancet II, 727.

Chapel TA, Burns RE. Oral contraceptives and exacerbations of lupus Erythematosus. Am J Obstet Gynecol 1971; 110: 366-369.

Schleicher EM. LE cells after oral contraceptives. Lancet 1968; 1: 821-822.

Spiera H, Plotz CM. Rheumatic symptoms and oral contraceptives. Lancet 1969; 1: 571-572.

McKenna CH, Weiman KC, Schulman LE. Oral contraceptives, rheumatic diseases, and autoantibodies. Arthritis Rheum 1969; 12: 313-314.

Garovich M, Agudelo C, Pisko E. Orla contraceptives and systemic lupus Erythematosus. Arthritis Rheum 1980; 23: 1396-1398.

Jungers P, Dougados M, Pelissier C, Nahoul K, Tron F, Bach JF. Infl uence of oral contraceptives therapy on the activity of systemic lupus Erythematosus. Arthritis Rheum 1982; 25: 618-623.

Beaumont JL, Lemort N, Lorenzelli EL, Delplanque B, Beaumont V. Antiethinyloestradiol antibody activities in oral contraceptive users. Clin exp Immunol 1979; 38: 445.

Beaumont V, Lemort N, Beaumont JL. Oral contraception, circulating immune complexes, antiethinylestradiol antibodies and thrombosis. Am J reprod. Immunol 1982; 2: 8.

Lahita RG, Bradlow HL, Kunkel HG, Fishman J. Anterations of estrogen metabolism in systemic lupus Erythematosus. Arthritis Rheum 1979; 22: 1195.

Lahita RG, Bradlow HL, Kunkel HG, Fishman J. Increased 16α-hydroxylation of estradiol in systemic lupus Erythematosus . J Clin Endocrinol Metab 1981; 53, 174.

Bucala R, Fishman J, Cerami A. Formation of covalent adducts between cortisol and 16α- hydroxyestrone and protein: possible role in the pathogenesis of cortisol toxicity and systemic lupus Erythematosus. Proc natn Acad Sci. USA 1982; 79: 3320.

Bucala R, Fishman J, Cerami A. The reaction of 16α-hydroxyestrone with erythrocytes in vitro and in vivo. Eur J. Biochem 1984; 140: 593.

Bucala R, Lahita RG, Fishman J, Cerami C. increased levels of 16α- hydroxyestrone modifi ed proteins in pregnancy and in systemic lupus erytematosus. J. Clin Endocrinol . Metab 1985; 60:841.

Lahita RG, Bucala R, Bradlow HL, Fishman K. Determination of 16ΑOHE-hydroxyestrone by RIA in systemic lupus Erythematosus. Arthritis. Rheum 1985; 28: 1122.

Bucala R, Ulrich PC, Chait BT, Bencsath FA, Cerami A. Structure of Lysine adducts with 16α-hydroxyestrone and cortisol. J. Steroid. Biochem 1986; 25: 127.

Bucala R, Lahita RG, Fishman J, Cerami A. Antioestrogen antibodies in users of oral contraceptives and patients with systemic lupus Erythematosus. Clin. Exp. Immunol 1987; 67: 167-175.

http://www.harpercollins.com/authors/19394/Robert_G_Lahita/index.aspx (consultado 29 agostode 2010).

http://fotos.lne.es/fotos/noticias/ 318×200/2009- 11-15_IMG_2009-11-08_01.35.50__3145174.jpg (consultado 17 septiembre de 2010).

Talal N. Natural history of murine lupus. Modulation by sex hormones. Arthritis Rheum. 1978 Jun; 21(5 Suppl):S58-63.

Talal N. Immunologic and viral factors in the pathogenesis of systemic lupus erythematosus. Arthritis Rheum 1970, 13: 887-893.

Levy JA. Autoimmunity and neoplasia: the possible role of C-type viruses. Am J Clin Pathol, 1974, 62: 258-280.

Howie JB, Helyer BJ. The immunology and pathology of NZB mice. Adv Immunol; 1968, 9: 215-266.

Evans MM, Williamson WG, Irvine WJ. The appearance of immunological competence at an early age in New Zealand black mice. Clin Exp Immunol 1968; 3: 375-383.

Steinberg AD, Baron SH, Talal N. The pathogenesis of autoimmunity in New Zealand mice. 1. Induction of antinucleic acid antibody in polyinosinic. Polycytidylic acid. Proc Nat Acad Sci USA; 1969, 63: 1102-1107.

Staples PJ, Steinberg AD, Talal N. Induction of immunological tolerance in older New Zealand mice repopulated with young spleen, bone marrow, or thymus. J Exp Med ; 1970, 131: 123-128.

Shirai T, Mellors RC: Natural cytotoxic autoantibody and reactive antigen in New Zealand Black and other mice. Proc Nat Acad Sci USA; 1971, 68: 1412-1415.

Barthold DR, Kysela S, Steinberg AD. Decline in suppressor T cell function with age in female NZB mice. J Immunol; 1974, 112: 9-16.

Burnet FM, Holmes MC. The natural history of the NZB/NZW F1 hybrid mouse: a laboratory model of systemic lupus erythematosus. Australas Ann Med. 1965 Aug; 14(3): 185-91.

Roubinian JR, Papoian R, Talal N. Androgenic hormones modulate autoantibody responses and improve survival in murine lupus. J Clin Invest. 1977 Jun; 59(6):1066-70.

Steinberg AD, Melez KA, Raveche ES, et al. Approach to the study of the role of sex hormones in autoimmunity. Arthritis Rheum. 1979 Nov; 22(11):1170-6.

N Talal. “Animal models for systemic lupus Erythematosus”, en Clin Rheum Dis, 1951; 1: 485.

N Talal, “Sex steroid hormones and systemic lupus Erythematosus”, en Arthritis Rheum, 1981, 24: 1054.

N Talal, M Dauphinée, SA Ahmed, P Christadoss, “Sex factors in immunity and autoimmunity. In: Progress in immunology V Y Yamamura and T Tada, (EDS.) New York Academic Press, 1983:1589-1600.

SA Ahmed, MJ Dauphinee, N Talal, “Effects of shortterm administration of sex hormones on normal and autoimmune mice”, en J Immunol, 1985; 134: 204 69. Eidinger D, Garrett TJ. Studies of the regulatory effects of the sex hormones on antibody formation and stem cell differentiation. J Exp Med. 1972 Nov 1; 136(5):1098-116.

Lahita RG, Bradlow HL, Kunkel HG, Fishman J. Alterations of estrogen metabolism in systemic lupus erythematosus. Arthritis Rheum. 1979 Nov; 22(11):1195-8.

Lahita RG, Bradlow HL, Kunkel HG, Fishman J. Increased 16 alpha-hydroxylation of estradiol in systemic lupus erythematosus. J Clin Endocrinol Metab. 1981 Jul; 53(1):174-8.

Stern R, Fishman J, Brusman H, Kunkel HG. Systemic lupus erythematosus associated with klinefelter›s syndrome. Arthritis Rheum. 1977 Jan- Feb; 20(1):18-22.

Schleicher EM: LE cells after oral contraceptives. Lancet 1968, 1:821-822.

Garovich M, Agudelo C, Pisko E: Oral contraceptives and systemic lupus erythematosus. Athritis Rheum 1980, 23:1396-1398.

Jungers P, Dougados M, Pelissier C, Nahoul K, Tron F, Bach J-F: Infl uence of oral contraceptive therapy on the activity of systemic lupus erythematosus. Arthritis Rheum 1982, 25: 618-623.

Sánchez-Guerrero J, Uribe AG, Jiménez-Santana L, et al. A trial of contraceptive methods in women with systemic lupus erythematosus. N Engl J Med. 2005 Dec 15; 353(24):2539-49.

Petri M, Kim MY, Kalunian KC, et al. Combined oral contraceptives in women with systemic lupus erythematosus. N Engl J Med. 2005 Dec 15;353(24):2550- 2558.

Buyon JP, Petri MA, Kim MY, et al. The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: a randomized trial. Ann Intern Med. 2005 Jun 21; 142(12 Pt 1):953-62.

Buyon JP. Hormone replacement therapy in postmenopausal women with systemic lupus erythematosus. J Am Med Womens Assoc. 1998 Winter;53(1):13-7.

http://www.lupus.org/webmodules/webarticlesnet/articlefiles/146-buyonj01.gif (consultado el 01 Octubre2010).

http://www.hopkins-arthritis.org/arthritiscenter/images/low%20res%20pics/PETRI.jpg (consultado el 01 Octubre 2010)

Cómo citar

[1]
Peñaranda-Parada, Édgar et al. 2010. HISTORIA SOBRE EL PAPEL DE LAS HORMONAS Y LOS ANTICONCEPTIVOS EN EL LUPUS. Medicina. 32, 4 (dic. 2010), 322–336.

Descargas

Los datos de descargas todavía no están disponibles.

Descargas

Publicado

2010-12-04

Número

Sección

Artículos de Revisión